QJM 2003;96:35-43. Aliment Pharmacol Ther 1993;7:281-6. Clin Infect.Dis. Ilhan A, Uz E, Kali S, et al. The comparative clinical efficacy of pyrophosphate/triclosan, copolymer/triclosan and zinc citrate/triclosan dentifrices for the reduction of supragingival calculus formation. 2007;25(1):67-74. 2008;18(2):101-103. J Health Popul.Nutr 2008;26(2):151-162. Zinc Against Plasmodium Study Group. Eur.J Clin Nutr 2008;62(10):1215-1223. The Recommended Dietary Allowance of zinc varies, but generally about 9-11 milligrams is enough for adults. Gupta, D. N., Mondal, S. K., Ghosh, S., Rajendran, K., Sur, D., and Manna, B. Zaichick VYe, Sviridova TV, Zaichick SV. Am J Clin Nutr 2002;76:805-12.. View abstract. Pediatr Clin North Am 2009;56(6):1343-1361. Lagiou P, Wuu J, Trichopoulou A, et al. A double-blind randomized trial. Moore, R. Bleeding gastric erosion after oral zinc sulphate. Powell-Beard L, Lei KY, Shenker L. Effect of long-term oral contraceptive therapy before pregnancy on maternal and fetal zinc and copper status. View abstract. View abstract. Ann Intern Med 2000;133:245-52. Arch Dermatol 2000;136:755-7. ( 3) Am J Med Sci 1981;282:68-74. View abstract. Attention deficit-hyperactivity disorder (ADHD). View abstract. Plasma uptake of manganese as affected by oral loads of manganese, calcium, milk, phosphorus, copper, and zinc. [Comparative study of 3 drugs (aceglutamide aluminum, zinc acexamate, and magaldrate) in the long-term maintenance treatment (1 year) of peptic ulcer]. View abstract. Alterations in calcium, magnesium, iron, and zinc metabolism by dietary cholestyramine. Exp Clin Endocrinol Diabetes. Leprosy. Singh BB, Udani J, Vinjamury Sp, et al. Antioxidant supplement and long-term reduction of recurrent adenomas of the large bowel. Here's a quick rundown of some of the best alternative sweeteners out there: Stevia: Stevia is a natural sweetener that comes from a plant in the Asteraceae family. Heyman, H., Van De Looverbosch, D. E., Meijer, E. P., and Schols, J. M. Benefits of an oral nutritional supplement on pressure ulcer healing in long-term care residents. Baum, M. K., Lai, S., Sales, S., Page, J. View abstract. View abstract. Mahyar A, Ayazi P, Ahmadi NK, et al. There are some excellent natural sweeteners that serve as tasty alternatives and don't come with a list of potential side effects and dangers. View abstract. View abstract. Dr. Ranjit Chandra, who was a pediatrician and immunologist at the Memorial University of Newfoundland, and who more recently formulated vitamin and mineral products for the Javaan Corporation in the United States, first addressed the problem of zinc overdoses when taking large amounts of zinc was popular, in the 1980's, pointed out that zinc deficiency was (and is) a common nutritional problem in North America, especially among older adults. Competitive inhibition of iron absorption by manganese and zinc in humans. Am J Clin Nutr 1993;57:673-8. Effect of micronutrient supplementation on infection in institutionalized elderly subjects: a controlled trial. View abstract. View abstract. J Matern Fetal Neonatal Med. Am J Clin Nutr. 2010;21(3):237-246. J Adolesc Health Care 1987;8:400-6. All rights reserved. Compend Contin Educ Dent 1998;19:4-15. View abstract. 4:03CV0146. zero sugars availability in many forms Stevia cons Some potential disadvantages to using stevia sweeteners include: Side effects. Dalgic, N., Sancar, M., Bayraktar, B., Pullu, M., and Hasim, O. Probiotic, zinc and lactose-free formula in children with rotavirus diarrhea: are they effective? View abstract. Oral zinc supplementation decreases the risk of HCC development in patients with HCV eradicated by DAA. View abstract. View abstract. Fajolu, I. Stevia doesn't have all the side effects associated with other no-calorie sweeteners. Klin.Wochenschr. Fischer Walker, C. L. and Black, R. E. Micronutrients and diarrheal disease. Treatment of Wilson's disease with zinc: XI. A community-based randomized controlled trial of iron and zinc supplementation in Indonesian infants: effects on growth and development. Antimicrob Agents Chemother 1984;25:20-4. 7. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Urol Res 1984;12:213-5. View abstract. Uebayashi H, Hatanaka T, Kanemura F, Tonosaki K. Acute anosmia in the mouse: behavioral discrimination among the four basic taste substances. Zinc is found throughout the body . Oral zinc as an adjunct to dapsone in lepromatous leprosy. Pediatrics 1999;103(4):e42. "There was no convincing evidence that non-nutritive sweeteners had any effect in adults on eating behavior, cancer, cardiovascular disease, kidney disease, mood, behavior or cognition. Fuller NJ, Bates CJ, Evans PH, Lucas A. View abstract. Golik A, Modai D, Weissgarten J, et al. Pediatrics. Kimmel, P. Zinc and chronic renal disease. Infants born weighing less than 2500 grams (5 pounds, 8 ounces). Taneja, S., Bhandari, N., Bahl, R., and Bhan, M. K. Impact of zinc supplementation on mental and psychomotor scores of children aged 12 to 18 months: a randomized, double-blind trial. However, due to the potential side effects associated with excess zinc consumption, its best not to exceed the upper limit of 40 mg per day unless under medical guidance and supervision (34). View abstract. Zinc supplement use and risk of prostate cancer. View abstract. Patel, A. Hillstrom L, Pettersson L, Hellbe L, et al. Taking zinc by mouth does not improve sexual function in males with sexual dysfunction related to kidney disease. Mousavi SM, Mofrad MD, do Nascimento IJB, Milajerdi A, Mokhtari T, Esmaillzadeh A. Taking zinc by mouth might help. 9. An.Pediatr.(Barc.) View abstract. View abstract. View abstract. Zinc is a very important mineral but you only need to take just enough. Nutr Metab Cardiovasc Dis. Effect of High-Dose Zinc and Ascorbic Acid Supplementation vs Usual Care on Symptom Length and Reduction Among Ambulatory Patients With SARS-CoV-2 Infection: The COVID A to Z Randomized Clinical Trial. The effect of chelating agents on the excretion of endogenous metals. Trial of zinc supplements in relation to pregnancy outcomes, hematologic indicators, and T cell counts among HIV-1-infected women in Tanzania. The body is programmed to release insulin when your mouth tastes "sweetness," so if there is no sugar for the insulin to metabolize, I'd worry that it would remain in the blood stream and potentially lead to hypoglycemia, which comes with side effects of anxiety and hunger. View abstract. Hyun TH, Barrett-Connor E, Milne DB. View abstract. van Leeuwen R, Boekhoorn S, Vingerling JR, et al. Ertekin, M. V., Koc, M., Karslioglu, I., and Sezen, O. Zinc sulfate in the prevention of radiation-induced oropharyngeal mucositis: a prospective, placebo-controlled, randomized study. American Rhinologic Society 49th Annual Fall Scientific Meeting abstract. In one case, a woman who took 400 mg of zinc a day became almost totally depleted of copper; her copper levels fell to 7 micrograms/dl, compared to an average of 70 to 155 micrograms/dl. It's best known as a natural sweetener. Mol Cell Biochem 1998;188:63-9. How much zinc you should take per day depends on your dietary intake and the type of supplement you choose, since supplements can contain different amounts of elemental zinc. Lalles J-P.Intestinal alkaline phosphatase: multiple biological roles in maintenance of intestinal homeostasis and modulation by diet. Nutr Rev. Whitney E, Cataldo CB, Rolfes SR, eds. Cornea 1996;15(6):582-588. View abstract. Treatment of Wilson disease with ammonium tetrathiomolybdate. J Nutr 1989;119:48-53. Douglas RM, Miles HB, Moore BW, et al. Hemil H, Petrus EJ, Fitzgerald JT, Prasad A. Zinc acetate lozenges for treating the common cold: an individual patient data meta-analysis. View abstract. But people who take lower levels of zinc can also experience zinc toxicity and zinc supplement side effects. Medicina (Kaunas). 2012 Feb;105(2):39-40, 42. View abstract. Zinc supplementation in infants born small for gestational age reduces mortality: a prospective, randomized, controlled trial. Bredholt M, Frederiksen JL. Devel Pharmacol Ther 1982;5:109-13. Rasker JJ, Kardaun SH. Sharquie, K. E., Khorsheed, A. Bullous lesions in acrodermatitis enteropathica. Khanna VJ, Shieh S, Benjamin J, et al. Sachdev, H. P., Mittal, N. K., and Yadav, H. S. Oral zinc supplementation in persistent diarrhoea in infants. Li Z, Li B, Song X, Zhang D. Dietary zinc and iron intake and risk of depression: A meta-analysis. Read more. Khedun SM, Naicker T, Maharaj B. Zinc, hydrochlorothiazide and sexual dysfunction. Nouri M, Chalian H, Bahman A, et al. Zinc may reduce the duration of cold symptoms, support blood sugar management, improve severe and inflammatory acne, decrease heart disease risk, and slow the progression of macular degeneration. View abstract. A randomized controlled trial of zinc as adjuvant therapy for severe pneumonia in young children. BMJ 2002;324:1358. View abstract. View abstract. This article explains everything you need to know about mineral, Acne surfaces during times of hormonal imbalance. This copyrighted material is provided by Natural Medicines Comprehensive Database Consumer Version. Zinc might decrease how much antibiotic the body absorbs from the gut. of copper every day, to keep zinc and copper in balance. Hustead, V. A., Greger, J. L., and Gutcher, G. R. Zinc supplementation and plasma concentration of vitamin A in preterm infants. Moyle G, Else L, Jackson A, Back D, Yapa MH, Seymour N, Ringner-Nackter L, Karolia Z, Gazzard B, Boffito M. Coadministration of atazanavir-ritonavir and zinc sulfate: impact on hyperbilirubinemia and pharmacokinetics. Ann Pharmacother 1995;29;1302. Chew EY, Clemons TE, Agrn E, Sperduto RD, Sangiovanni JP, Kurinij N, Davis MD; Age-Related Eye Disease Study Research Group. Wound Repair Regen. View abstract. View abstract. Palomo F, Wantland L, Sanchez A, Volpe AR, McCool J, DeVizio W. The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: a six month clinical study. Henkin RI, Martin BM, Agarwal RP. help if you have any side effects that bother you or do not go away. Iran J Kidney Dis. Shankar AH, Prasad AS. Simkin PA. http://ods.od.nih.gov/factsheets/Zinc-QuickFacts/" (2012): 3. View abstract. Healthline Media does not provide medical advice, diagnosis, or treatment. Last updated on Sep 6, 2022. Am J Clin Nutr 2005;82(3):605-610. View abstract. 2005;9(12):1378-1384. 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